Ozanimod Hydrochloride | ||||
CAS NO.: | 1618636-37-5 | |||
Chemical Formula: | C23H25ClN4O3 | |||
Molecular Weight: | 440.9000 | |||
DMF&GMP status: | Please contact us for more details. | Description: |
Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene(now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26 2020. MS is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Inflammatory bowel disease also a chronic inflammatory condition and can cause persistent abdominal pain, diarrhea, bloody stools, and vomiting. In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard in MS therapy. Studies involving patients with inflammatory bowel disease have also shown promising results.
**The products protected by patents in this product catalog are used for laboratory analysis, research and development, and cannot be sold to any country or region with patent protection and for commercial purpose. If the resulting patent infringement risks and responsibilities will be borne by the buyer. |
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Approvals | ||||
Active Ingredient | Dosage Form; Route | Strength | Proprietary Name | Applicant |
OZANIMOD HYDROCHLORIDE | CAPSULE;ORAL | 0.23MG | ZEPOSIA | CELGENE INTERNATIONAL II SARL |
OZANIMOD HYDROCHLORIDE | CAPSULE;ORAL | 0.46MG | ZEPOSIA | CELGENE INTERNATIONAL II SARL |
OZANIMOD HYDROCHLORIDE | CAPSULE;ORAL | 0.92MG | ZEPOSIA | CELGENE INTERNATIONAL II SARL |
Patent Data | ||||
Patent No. | Patent Expiration | Drug Substance Claim | Drug Product Claim | Patent Use Code |
8481573 | 05/14/2029 | DS | DP | U-2774 |
8796318 | 05/14/2029 | DS | DP | |
9382217 | 05/14/2029 | U-2774 | ||
Exclusive Data | ||||
Exclusivity Code | Exclusivity Expiration | |||
NCE | 03/25/2025 | |||